Saturday 04 May 2024
Internal Reference Number: FOI_7726
Date Request Received: 05/02/2024 00:00:00
Date Request Replied To: 06/02/2024 00:00:00
This response was sent via: By Email
Request Summary: Request for ALT/AST data
Request Category: Health
| Question Number 1: Normal ranges of liver function tests - This information should be readily available through your clinical biochemistry or pathology department. I would be grateful if you could provide me with the following: The normal range (adults and children) for the following liver enzymes: alanine transaminase (ALT), aspartate transaminase (AST), alkaline phosphatase and gamma GT. | |
| Answer To Question 1: GGT Male: <60 U/L Female: <40 U/L ALT Male: 10-50 U/L Female: 10-35 U/L ALP Males 0-14 d 83-248 U/L 15d-<1yr 122-469 U/L 1yr - <10yr 142-335 U/L 10-<13yrs 129-417 U/L 13-<15yrs 116-468 U/L 15-<17yrs 83-331 U/L 17-<19yrs 55-149 U/L 19-110yrs 40-129 U/L Females 0-14 d 83-248 U/L 15d-<1yr 122-469 U/L 1yr - <10yr 142-335 U/L 10-<13yrs 129-417 U/L 13-<15yrs 57-254 U/L 15-<17yrs 50-117 U/L 17-<19yrs 45-87 U/L 19-110yrs 35-104 U/L AST Male: 10-50 U/L Female: 10-35 U/L Paediatric ranges are not quoted for ALT, GGT, AST. | |
| Question Number 2: The method and machine used with reference so it can be identified. | |
| Answer To Question 2: Roche Cobas c702 module using photometric assays. | |
| Question Number 3: How was your local normal range determined? a. From the reference range specified by the manufacturer b. By the lab of a large group of normal volunteers c. From historical data d. Other – please describe. | |
| Answer To Question 3: Manufacturers reference range used. | |
| Question Number 4: Do your liver function tests automatically include measurement of AST? | |
| Answer To Question 4: No | |
| Question Number 5: How many sets of liver function tests, which include measurement of ALT and alkaline phosphatase, does your hospital or laboratory complete each year? How many patients does this represent? | |
| Answer To Question 5: 92,586 requests in 2022-23 (not possible to give patient numbers) | |
| Question Number 6: How many requests for measurement of AST does your hospital or laboratory complete each year? How many patients does this represent? | |
| Answer To Question 6: 1,898 requests in 2022-23 (not possible to give patient numbers) | |
| Question Number 7: How many values exceed the upper limit of normal for each liver function test? | |
| Answer To Question 7: Data Not Available | |
| Question Number 8: If you do not hold this information because you consider the analyses to be done externally by an outside laboratory, please provide the name of the laboratory and email address for their FOI officer. | |
| Answer To Question 8: Not Applicable | |
| To return to the list of all the FOI requests please click here |
Our staff at Salisbury District Hospital have long been well regarded for the quality of care and treatment they provide for our patients and for their innovation, commitment and professionalism. This has been recognised in a wide range of achievements and it is reflected in our award of NHS Foundation Trust status. This is afforded to hospitals that provide the highest standards of care.
